| dc.description.abstract | Background: Infection with malaria under five remains a burden in sub Saharan African, and
is associated with numerous preventable deaths. The clinical outcome of Plasmodium
infection in endemic areas is influenced by erythrocyte polymorphisms including the ABO
blood groups. This study reports the association of Malaria with the ABO blood group in
children under 5years attending the outpatient‟s clinic at Bundibugyo hospital.
Methods: This was a cross-sectional prospective study that carried out during the months of
July to August, 2018, in Bundibugyo hospital. The study population comprised of children 7
months-5 years presenting with a febrile condition. Clinical and laboratory investigations
were done using malaria rapid diagnostic tests and microscopy; Blood grouping was done by
hemagglutination methods. Statistical analysis was done at bivariate and multivariate levels
using SPSS Version 23.0 and P-values less than 0.05 were considered significant.
Results: The prevalence of malaria was 14%. The most predominant blood group type were
Rhesus (D) positive „O‟ at 54%; A‟ at 26.2%, B‟ at 18.6% and AB‟ at 1.3%;. Blood group A
were 1.24 times more susceptible to have positive malaria test than those with blood group O
(OR= 1.24, 95%C.I (1.01 – 2.48) ; P-value =0.003. B were 1.29 times more susceptible to
have positive malaria test than those with blood group O blood (OR= 1.29, 95% C.I (0.88 –
3.23 ); P-Value = 0.011). The statistically outcome indicated that: blood groups A and B
patients are more likely to have a positive malaria test compared to blood group O | en_US |
