Browsing by Author "Ndeze, Ivan"

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    Assessment of the diagnostic performance of TrueHb ® point-of-care hemometer compared with Sysmex i3 analyzer among patients at International Hospital Kampala, Uganda
    (Dove Press, 2019-04-01) Taremwa, Ivan Mugisha; Ndeze, Ivan; Mwambi, Bashir; Atuhairwe, Christine; Achieng, Diana Inda; Natukunda, Bernard
    Aim/Objective: To assess the diagnostic performance of TrueHb ® point-of-care (POC) hemometer compared with Sysmex i3 analyzer at International Hospital Kampala, Uganda. Materials and methods: We analyzed ethylenediaminetetraacetic acid blood samples to estimate hemoglobin (Hb) levels using parallel testing with TrueHb ® hemometer and Sysmex i3 analyzer. Data were analyzed to ascertain the diagnostic performance of the test assays using the Bland and Altman method. Sensitivity, specificity, positive and negative predictive values were calculated. Results: The study enrolled 402 patients; of these, 156 (38.8%) were males. The average Hb levels were 8.7±1.8 and 13.3±2.6 g/dL for the anemic and nonanemic patients, respectively. One hundred and fifty-five participants were anemic, giving anemia prevalence of 38.56% (95% CI: 35.17–40.38). The mean difference of the TrueHb ® and Sysmex i3 assays was 2.2219 (SD 1.07915), and the two devices did not show a difference in their measurements (t=−2.407, p-value 0.017, 95% CI: −0.095–0.010). Further, they showed a significant level of agreement (t=41.281; 95% CI: 2.1161–2.3277) and intraclass correlation coefficients (ICC=0.793). The sensitivity, specificity, positive and negative predictive values were 100.00%, 51.01%, 55.16% and 100.00%, respectively. The average performance turnaround time (TAT) for the TrueHb ® hemometer was 2.46 mins (95% CI: 2.37–2.55). Conclusion: TrueHb ® POC hemometer is an accurate POC for Hb estimation with a good performance agreement with the Sysmex i3 analyzer. This, coupled with its utility aspects, makes it a good diagnostic tool in a high anemia burden and low-resource setting.
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    Assessment Of Truehb ® Point-Of-Care Hemometer Among Patients Attending International Hospital Kampala
    (International Health Sciences University., 2018-12) Ndeze, Ivan
    Background: Accurate determination of hemoglobin (Hb) levels is vital to elucidate the extent of anemia, and thus a guide to clinical and research care in harnessing timely diagnosis. This study assessed the diagnostic performance of TrueHb ® point-of-care hemometer at International Hospital Kampala, Uganda. Methods: We analyzed ethylene-di-amine tetra acetic acid (EDTA) blood samples to estimate Hb levels using parallel testing with TrueHb® hemometer and Sysmex i3 analyzer. Data was analyzed using STATA 12 (College Station, TX, USA) to ascertain diagnostic performance of the test assays using the Bland and Altman method. Sensitivity, specificity, positive and negative predictive values were calculated. Results: We analyzed 402 EDTA blood samples, the mean difference of the two methods was 2.2219 (SD 1.07915),p-value 0.017 The accuracy of the two assays as measured by the intra- class correlation coefficients (ICC), the average measure was 0.793, which indicated a substantial correlation between the two assays. The average performance TAT for the machine was 2.46 minutes (95% CI= 2.37-2.55) Conclusion: The TrueHb® point-of-care hemometer could be an accurate point of care tool for screening anemia with recalibration done positively by 2.22g/dl. The TAT for the TrueHb® meter is convenient.